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puma ignite
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Howar Cook(e)
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Dołączył: 22 Mar 2020
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ÿþWe recently reported a new UV-curable polyurethane-methacrylate (PUMA) puma fierce resin that has excellent qualities as a disposable microfluidic substrate for clinical diagnostic applications. This article discusses strategies to improve the production yield of PUMA chips that contain dense and high-aspect-ratio features, which presents unique challenges in demolding and bonding steps. These fabrication improvements were deployed to produce a microfiltration device that contained closely spaced and high-aspect-ratio columns.

We recently reported a new UV-curable polyurethane-meth-acrylate (PUMA) resin that is non-elastomeric and has excellent qualities as a disposable microfluidic substrate, especially for clinical diagnostic applications. 18 This PUMA substrate is transparent optically, resistant to biofouling, compatible with many chemicals encountered in microfluidic applications, curable rihanna puma creepers to a typical thickness (about the thickness of glass slides), bondable to form enclosed devices easily.

Certified by the supplier as United States Pharmacopeia (USP) Class VI-compliant, this PUMA resin has been tested thoroughly for its chemical inertness, fenty puma slides working temperature, biocompatibility, and sterilizability  all qualities necessary for manufacturing medical diagnostic devices.In this article, we focus on the back-end steps  demolding, bonding, and interconnecting to external fluidic delivery  of producing a PUMA chip. During demolding, high-aspect-ratio microstructures are prone to shear-induced damage.

Aclar sheets (Honeywell, Morristown, NJ), which is a polychloro-trifluoro-ethylene (PCTFE) polymer containing no plasticizer, may be used in lieu of cellophane in critical applications. To puma ignite form fluidic reservoirs or holes for external connection, PTFE posts (3 mm (D) × 3 mm (H)) were embedded in the PUMA resin before curing. The entire assembly was placed in a high-intensity UV source (ADAC Cure Zone 2 UV Flood Light Source, fitted with a 400W metal halide lamp.

PUMA resin; 3 : PTFE posts; 4 : polypropylene sheet; 5 : cellophane (or Aclar). ( B ) Two methods of interfacing PUMA chip with external tubing: 1 : PUMA chip; 2 : barb elbow connector; 3 : polyurethane tubing; 4 : additional resin to seal leak (Dymax 186M); 5 : PTFE tubing; 6 : polyolefin heat-shrink; 7 : retaining ring.Fig. 1B shows two examples of interfacing a PUMA chip for black puma external fluidic delivery. The left side of Fig. 1B illustrates the use of a barbed elbow connector.

UMA replica taken under a stereoscope (same pattern as Fig. 2A ), released from the mold without the assistance of the pulling station. Two types of defects were evident: (1) wavy walls, and (2) irregular vertical column spacings. The waviness of the wall is generally attributable to improper cleaning of the PDMS mold between replication runs, which increases the adhesion between the mold and the resin. Consequently it is not possible to lift apart [img] puma-579iiy.jpg[/img] without some horizontal motion to counter the adhesive force.
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